Eltrombopag Olamine ( Eltrombopag diethanolamine salt; SB-497115GR )

产品货号. M18653 CAS No. 496775-62-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Eltrombopag Olamine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity.
产品描述

Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
同义词

Eltrombopag diethanolamine salt; SB-497115GR
通路

Others
靶点

Other Targets
受体

Thrombopoietin receptor
研究领域

Cardiovascular Disease
适应症

——

CAS Number

496775-62-3
分子量

564.63
分子式

C29H36N6O6
纯度

98%
溶解度

DMSO : ≥ 50 mg/mL; 88.55 mM
SMILES

Cc1c(cc(cc1)n1c(=O)c(c([nH]1)C)N/N=C/1\C=CC=C(C1=O)c1cc(ccc1)C(=O)O)C.C(CO)N.C(CO)N
化学全称

——

1. Erickson-Miller CL, et al. Stem Cells, 2009, 27(2), 424-430.

计算器

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