Eltrombopag Olamine ( Eltrombopag diethanolamine salt; SB-497115GR )

产品货号. M18653 CAS No. 496775-62-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Eltrombopag Olamine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity.
产品描述

Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
同义词

Eltrombopag diethanolamine salt; SB-497115GR
通路

Others
靶点

Other Targets
受体

Thrombopoietin receptor
研究领域

Cardiovascular Disease
适应症

——

CAS Number

496775-62-3
分子量

564.63
分子式

C29H36N6O6
纯度

98%
溶解度

DMSO : ≥ 50 mg/mL; 88.55 mM
SMILES

Cc1c(cc(cc1)n1c(=O)c(c([nH]1)C)N/N=C/1\C=CC=C(C1=O)c1cc(ccc1)C(=O)O)C.C(CO)N.C(CO)N
化学全称

——

1. Erickson-Miller CL, et al. Stem Cells, 2009, 27(2), 424-430.

计算器

产品手册

关联产品

Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
Acacetin 7-[rhamnosy...

The fruits of Fortunella japonica.
UNC 3230

UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C.